In vitro Evaluation of Antibacterial and Antifungal Activities of Chrysophyllum albidum Stems Bark

The aim of this study was to evaluate the antibacterial and antifungi activities of ethanolic and methanolic extracts from Chrysophyllum albidum stem bark. The crude extracts were screened against Staphylococcus aureus, Escherichia coli, Klebsiella, Candida albicans and Aspergillus niger at different concentrations (3.125 mg/mL, 6.25 mg/mL, 12.5 mg/mL, 25 mg/mL, 50 mg/mL and 100 mg/mL) using the agar well diffusion technique. The ethanolic extracts had stronger inhibitory effects on test organisms than the methanolic extracts. The antimicrobial activity observed with the ethanolic extract ranged between 10 and 21.5 mm with no detectable activity on Aspergillus niger. Stronger antimicrobial activity was observed with the methanolic crude extracts at all concentrations with all test organisms. The result of this study is indicative that C. albidum stem bark extracts can be used in the treatment of infections.