Efficacy of early oral refeeding in patients of mild acute pancreatitis

Objective: To compare Early Oral Refeeding (EORF) with Routine Oral Refeeding (RORF) on outcome of patients of mild Acute Pancreatitis (AP) in terms of Mean Length of Hospital Stay (LOHS).

Methods: This randomized controlled trial was conducted at Surgical Department CMH Rawalpindi, from 1st Feb 2015 to 01st Aug 2016. A total of 60 patients with pain epigastrium were enrolled in the study. Severity of pancreatitis was assessed using Glasgow Scale. Patients were randomly divided in two groups. Group-A was started feeding within 12 hours (EORF group) and Group-B after 12 hours (RORF group). Demographic details and data were recorded on a structured proforma. After discharge, LOHS was measured for both groups and outcome was compared.

Results: The groups were comparable with respect to age, sex, etiology, Glasgow Scale, time from onset of pain and Serum Amylase levels at admission. Treatment was standardized according to international guidelines for both groups. The mean LOHS was 7.8 ± 2.14 days in the Group-A and 10.03 ± 1.75 days in Group-B. The difference in the mean LOHS between the two groups was statistically significant (p<0.05).

Conclusion: In patients of mild acute pancreatitis, early oral feeding is feasible and safe and has better outcome then those with routine oral refeeding.