Overview on Acute Poststreptococcal Glomerulonephritis in Pediatrics: A Review

Fadl, Ahmed Abdelsamie and Aldubaib, Hiba Saud H. and Alzayyat, Nof Tarq F. and Alzahrani, Mohammed Abdullah S. and Mohammed A., Alshammasi, Mustafa and Alabbad, Fatimah Arif S. and Alanzl, Ashjan Aqeel Q. and Haeider A, Al Jalooud, Hassan and Alrefaei, Aseel Saud S and Alattas, Mohammed Marwan Ahmed (2021) Overview on Acute Poststreptococcal Glomerulonephritis in Pediatrics: A Review. Journal of Pharmaceutical Research International, 33 (57A). pp. 34-39. ISSN 2456-9119

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Abstract

Acute poststreptococcal glomerulonephritis (APSGN) is the most common kind of post-infectious glomerulonephritis and is caused by group A streptococcus (Streptococcus pyogenes). Although the prevalence of PSGN has decreased in affluent nations, non-streptococcal species are becoming more common. and it is still the major cause of glomerulonephritis in children. APSGN can manifest itself in epidemic outbreaks or clusters of instances, as well as in single persons. Epidemic outbreaks have previously been documented as a result of upper respiratory or cutaneous streptococcal infections in various parts of the world. In developed nations, APSGN is now mostly a disease of the elderly, who are more likely to have disabling illnesses such as cancer, alcoholism, or diabetes. Children between the ages of 3 and 12 (with a peak incidence between the ages of 5 and 6 years) and seniors over the age of 60 are the most commonly affected. The pathophysiology of APSGN is complicated by inflammation. (APSGN) often occurs one to two weeks after a throat infection and three to five weeks after a skin infection. Hematuria, edoema, azotemia, and hypertension are the most common clinical signs. Loop or thiazide diuretics, are the most effective therapy for hypertension and edoema in PSGN. In this review we’ll be looking at the disease causes, epidemiology, presentation and treatment.

Item Type: Article
Subjects: STM Digital > Medical Science
Depositing User: Unnamed user with email support@stmdigital.org
Date Deposited: 14 Feb 2023 10:55
Last Modified: 29 Jun 2024 12:41
URI: http://research.asianarticleeprint.com/id/eprint/59

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