Denisuk, T. A. and Pokrovskii, M. V. and Philippova, O. V. and Gudyrev, O. S. and Pokrovskaya, T. G. and Korokin, M. V. and Osipova, O. A. (2015) Endotelioand cardioprotective effects of HMG-Co-A reductase in endotoksininducing endotelial dysfunction. Kuban Scientific Medical Bulletin, 5. pp. 51-55.
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Abstract
The use of inhibitors of HMG-Co-A reductase inhibitor simvastatin, atorvastatin, rosuvastatin and nanoparticulative rosuvastatin on background modeling endotoksininducing pathology, introduction of strain 603 Staphylococcusaureus leads to the development of dose-response endotelioprotectiv action, expressed in the normalization of QED, prevent increase adrenoreactivity and exhaustion of myocardial reserve and and normalization of biochemical markers of inflammation (C-reactive protein) and the level of proinflammatory cytokines. When this is detected positive dynamics and-products of NO and expression of eNOS.
Item Type: | Article |
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Subjects: | STM Digital > Medical Science |
Depositing User: | Unnamed user with email support@stmdigital.org |
Date Deposited: | 08 Apr 2023 08:12 |
Last Modified: | 02 Oct 2024 07:24 |
URI: | http://research.asianarticleeprint.com/id/eprint/516 |