Fosfomycin, a therapeutic option for infections produced by multiple drug-resistant Enterobacteriaceae

Yeganeh Sefidan, Fatemeh and Azargun, Robab and Ghotaslou, Reza (2016) Fosfomycin, a therapeutic option for infections produced by multiple drug-resistant Enterobacteriaceae. Microbiology Research, 7 (1). ISSN 2036-7473

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Abstract

Due to the increasing prevalence of infections caused by resistant bacteria and especially multiple drug resistance Enterobacteriaceae, availability of alternative effective antibiotics is restricted. The goal of this study was to investigate the susceptibility profile of multiple drug resistance and extensively drug resistance Enterobacteriaceae isolated from various clinical samples to fosfomycin. A total of 303 non-duplicate Enterobacteriaceae isolates were collected. Identification and susceptibility testing were done according to standard microbiological procedures and the Kirby-Bauer test, respectively. Of all isolates, 272 (89.8%) and 26 (8.6%) were detected as multiple drug resistance and extensively drug resistance strains, respectively. The most effective antibiotic (98%) was fosfomycin, when compared with other antibiotics against multiple drug resistance and extensively drug resistance Enterobacteriaceae isolates. In this study, we find high levels of resistance to commonly used antibiotics. However, fosfomycin can be a good option for treating multiple drug resistance Enterobacteriaceae.

Item Type: Article
Subjects: STM Digital > Medical Science
Depositing User: Unnamed user with email support@stmdigital.org
Date Deposited: 16 Jun 2023 09:05
Last Modified: 21 Sep 2024 04:51
URI: http://research.asianarticleeprint.com/id/eprint/1157

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