Synthesis and Biological Value of Thiouracils and Fused Thiouracils (A review)

Sayed, Mosad and Ahmed, Naglaa (2017) Synthesis and Biological Value of Thiouracils and Fused Thiouracils (A review). Journal of Advanced Pharmacy Research, 1 (2). pp. 75-88. ISSN 2357-0539

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Abstract

A literature survey revealed that the thiouracil derivatives and their condensed heterocycles have occupied a marked position as synthon for various biologically active compounds. They have a wide range of therapeutic uses that include anti-cancer, anti-microbial, molluscicidal, anti-leishmanial, anti-oxidant, anti-viral as anti-HIV and anti-HCV, and anti-thyroid activities. Numerous methods for the synthesis of thiouracils offer enormous scope in the field of medicinal chemistry. The review article aims to review the work reported for the synthesis and the biological activities of thiouracils and fused thiouracils from the past to recent years.

Item Type: Article
Subjects: STM Digital > Medical Science
Depositing User: Unnamed user with email support@stmdigital.org
Date Deposited: 12 Jun 2023 06:58
Last Modified: 05 Sep 2024 11:50
URI: http://research.asianarticleeprint.com/id/eprint/1108

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