Use of Human Embryonic Stem Cells (hESCs) in the Treatment of Glaucoma

Glaucoma is a degenerative, optic neuropathy that results in damage to the optic nerve due to increased intraocular pressure (IOP). IOP can be influenced by hypertension, body mass index, atherosclerotic disease and diabetes. Cell based therapies play an important role in treating eye diseases, especially (irreversible loss of cells) due to glaucoma. We used human embryonic stem cell (hESC) therapy in two patients with glaucoma. hESCs are derived from a patented technology and are in use since the last 13 years. After the therapy, patients showed signs of improvement in their sight such as in peripheral vision, as well as in cognitive abilities like concentration and speech.