Falcicchia, Chiara and Simonato, Michele and Verlengia, Gianluca (2018) New Tools for Epilepsy Therapy. Frontiers in Cellular Neuroscience, 12. ISSN 1662-5102
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Abstract
One third of the epilepsies are refractory to conventional antiepileptic drugs (AEDs) and, therefore, identification of new therapies is highly needed. Here, we briefly describe two approaches, direct cell grafting and gene therapy, that may represent alternatives to conventional drugs for the treatment of focal epilepsies. In addition, we discuss more in detail some new tools, cell based-biodelivery systems (encapsulated cell biodelivery (ECB) devices) and new generation gene therapy vectors, which may help in the progress toward clinical translation. The field is advancing rapidly, and there is optimism that cell and/or gene therapy strategies will soon be ready for testing in drug-resistant epileptic patients.
Item Type: | Article |
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Subjects: | STM Digital > Medical Science |
Depositing User: | Unnamed user with email support@stmdigital.org |
Date Deposited: | 02 Jun 2023 07:16 |
Last Modified: | 07 Jun 2024 11:01 |
URI: | http://research.asianarticleeprint.com/id/eprint/1001 |